Titia Sixma, Ph.D., is a group leader leading the Structural Biology laboratory at the Netherlands Cancer Institute in Amsterdam, member of the Oncode Institute and professor at Erasmus University Rotterdam in the Netherlands.

She is a structural biologist, an expert in the study of biological macromolecules that govern vital functions within cells and are important in cancer. Using a combination of crystallography and biochemistry methods, her group studies the form and function of proteins involved in DNA damage repair, providing fundamental knowledge for the design and synthesis of anti-cancer drugs. She is an elected member of the Royal Netherlands Academy of Arts and Sciences (KNAW), the Academia Europaea and the EMBO.